Consortium

Partner Organisation


In this consortium, partners who are experts in the best available imaging technologies and who are leading in biodegradable Mg based implants come together. By the combination of techniques and academic / non-academic background, MgSafe offers complementarity in the best possible way


HZG

Helmholtz-Zentrum Geesthacht Centre for Material and Coastal Research


Country: Germany
Dept./Division/Laboratory: Metallic Biomaterials WB
Scientist-in-Charge: Prof. Dr. R. Willumeit-Römer
Website: HZG Metallic Biomaterials

General description
The Helmholtz-Zentrum Geesthacht Centre for Material- and Coastal Research is one of 18 members of the Helmholtz Association of German Research Centres, Germany’s largest science organisation. HZG is located in Geesthacht near Hamburg with branches in Teltow near Berlin and in Hamburg and a total staff of approximately 950 employees.

Role in MgSafe

  • Coordinator
  • Work Package leader of WP5 and WP8
  • Host of ESRs 10 and 11: Hanna Słomińska and Kamila Iskhakova
  • Research topic: Mg-implants – from material design to in vivo application
  • Scientific part in MgSafe: Ex vivo Synchrotron measurements (WP3)

Contact:

  • Regine Willumeit-Römer (coordinator, supervisor ESRs)
  • Florian Wieland, Berit Zeller-Plumhoff (PIs)
  • Hans-Jörg Isemer (international projects officer HZG)
  • Katrin / Katharina Philipp (project manager)
  • Annette Havelberg (project officer)
  • Thorsten Fischer (chair dissemination board MgSafe)

 


CNR-IFC

Italian National Research Council - Institute of Clinical Physiology


Country: Italy
Dept./Division/Laboratory: Institute of Clinical Physiology IFC
Scientist-in-Charge: Prof. Dr. L. Menichetti
Website: CNR-IFC

General description
The Italian National Research Council Institute of Clinical Physiology is situated at Pisa. IFC operates in the context of the Department of Biomedicine and is the largest biomedical institute of CNR. CNR-IFC holds a privileged position in research and higher education, integrating three universities, the largest CNR (National Research Council) Campus in Italy, an internationally recognised University Hospital, and the G. Monasterio Foundation for Public Health and Medical Research. CNR-IFC is reference site for EuroBioImaging (www.eurobioimaging.eu). CNR-IFC cooperates with the School of Advanced Studies Sant’Anna, which provides a number of highly competitive scholarships from different founding organisations (www.santannaschool.eu).

Role in MgSafe

  • Work Package leader of WP2
  • Host of ESRs 6 and 7: Leon Riehakainen and Eduarda da Silva
  • Research topic: Biomarker development in the field of Mg-implants with multimodal and molecular imaging of bone regeneration
  • Scientific part in MgSafe: In vivo PET/(µ)CT and MRI (WP1) and biochemical/biohumoral assays (WP2)

Contact:

  • Luca Menichetti (supervisor ESRs)
  • Daniele Panetta, Giuseppina Basta, Serena del Turco, Claudia Kusmic, Debora Petroni (PIs)
  • Michela Rial (head of grant office)

 


MUG

Medical University of Graz


Country: Austria
Dept./Division/Laboratory: Orthopaedics and orthopaedic surgery
Scientist-in-Charge: Prof. Dr. A. Weinberg
Website: MUG Prof. A. Weinberg
                   MUG Musculo-Skelettale Forschungseinheit für Biomaterialen (German only)

General description
Sustainable health research is the central theme at the Medical University of Graz. The Austrian health university is characterised by sustainability in teaching, research and patient care with main focus on prevention and preservation of health. In parallel, the health university provides high-level patient care by training future doctors and nurses and research on innovative treatment methods and health-preserving measures. Not only do students gain from expert knowledge, so does the whole population. Postgraduate continuing education for doctors and other target groups completes the broad range of services.

Role in MgSafe

  • Work Package leader of WP1 and WP7
  • Host of ESRs 1 and 2: Begüm Okutan and Romy Marek
  • Research topic: Evaluation of Mg-based implant materials in small and large animal models
  • Scientific part in MgSafe: In vivo (µ)CT and fluorescence imaging (WP1)

Contact:

  • Annelie Weinberg (Supervisor ESRs)
  • Nicholas Donohue, Nicole Sommer (PIs)

 


UiO

University of Oslo


Country: Norway
Dept./Division/Laboratory: Faculty of Dentristry, Dept. of Biomaterials
Scientist-in-Charge: Prof. Dr. H. Haugen
Website: UiO Biomaterials

General description
Founded in 1811, the University of Oslo (UiO) is the highest ranked institution of education and research in Norway. UiO has over 27,000 students and 7,000 employees and is ranked 67th of the World’s Top 100 universities. With five Nobel Prize Winners, UiO has a strong track record of pioneering research and scientific discovery. The department of Biomaterials has a multidisciplinary team of clinicians, material engineers and biochemist. The most important contribution to innovation is made through the education of degree candidates, excellent research, and the exchange of knowledge with important stakeholders in society.

Role in MgSafe

  • Host of ESR 3: Maryam Rahmati
  • Research topic: Biomaterial and hard tissue reaction
  • Scientific part in MgSafe: Histological validation (WP1)

Contact:

  • Håvard J. Haugen, Janne E. Reseland (supervisors ESR)
  • S. Petter Lyngstaadas (co-supervisor ESR)
  • Hanna Tiainen (PI)

 


OsloMet

Oslo Metropolitan University


Country: Norway
Dept./Division/Laboratory: Optical/NIRS laboratory
Scientist-in-Charge: Assoc. Prof. Dr. P. Mirtaheri
Website: OsloMet optical/NIRS laboratory

General description
Oslo Metropolitan University is an urban university with a diverse academic profile and a clear international orientation. Through the research we conduct and the students we educate, OsloMet seeks to respond to the needs of society and the labour market. OsloMet is forward thinking and committed to adopting new technologies and innovative solutions that improve the way the university is run. OsloMet is Norway’s third largest education institution, with more than 20.000 students and 2.100 employees. The OsloMet AI Lab, opened by the Faculty of Technology, Art and Design in 2016, administers research and student projects in artificial intelligence, both applied and basic research, including theory and the use of machine learning in different areas. In 2009, OsloMet built its first optical/NIRS lab. The lab became part of a laboratory network at OsloMet with motion analysis lab and the research group Diagnostic technology and improved medicine DIAMED.

Role in MgSafe

  • Work Package leader of WP6
  • Host of ESR 8: Hafiz Wajahan Hassan
  • Research topic: Oxygenation/perfusion at the Mg-implant
  • Scientific part in MgSafe: In vivo Near Infrared Spectroscopy (WP2)

Contact:

  • Peyman Mirtaheri (PI, supervisor ESR)
  • Terje Gjøvaag (Co-supervisor ESR)
  • Lene Bomann-Larsen (Project officer)
  • Stig Nøra (Communication advisor)

 


MHH

Hannover Medical School


Country: Germany
Dept./Division/Laboratory: Preclinical Imaging Center
Scientist-in-Charge: Dr. M. Meier
Website: AG Meier (German only)

General description
The Preclinical Imaging Center at the Hannover Medical School is located in the central animal facility and offers support as a collaborating research unit.

Role in MgSafe

  • Host of ESR 5: Christina Yiannakou
  • Research topic: Unique imaging technologies for functional parameters
  • Scientific part in MgSafe: In vivo MRI development and inflammation monitoring (WP2)

Contact:

  • André Bleich (supervisor ESR)
  • Martin Meier (deputy supervisor, PI)

 


UGOT

University of Gothenburg


Country: Sweden
Dept./Division/Laboratory: Biomaterials
Scientist-in-Charge: Prof. Dr. P. Thomsen
Website: UGOT Biomaterials

General description
The University of Gothenburg meets societal challenges with diverse knowledge. 47 500 students and 6 000 employees make the University a large and inspiring place to work and study, with a continuous flow of new knowledge and ideas.

The biomaterials research area has a strong tradition and UGOT has recently been highlighted as the No 1 University globally in the field of osseointegration. The biomaterials research spans from materials across pre-clinical to clinical fields, particularly related to dental, orthopaedic and cardiovascular application areas. The Departments of Biomaterials and Experimental Biomedicine are major assets for experimental (animal) research, owning one of the most modern facilities in Northern Europe. The Department of Biomaterials is a partner in the Swedish Government Strategic funding Area of Advance in Materials Science, hosted by Chalmers University of Technology.

Role in MgSafe

  • Host of ESR 4: Heithem Ben Amara
  • Research topic: Evaluation of biological reactions around biomaterials
  • Scientific part in MgSafe: Molecular and structural analyses, histology (WP1)

Contact:

  • Peter Thomsen (supervisor ESR)
  • Anders Palmquist, Omar Omar (PIs, co-supervisors ESR)

 


WUT

Warsaw University of Technology


Country: Poland
Dept./Division/Laboratory: Materials Science and Engineering
Scientist-in-Charge: Prof. W. Święszkowski
Website: WUT Materials Design

General description
The Warsaw University of Technology is not only the oldest and largest but also the best technical university in Poland; in the ranking of Polish universities, it has taken the first place in its category for nine years. At WUT, over 180 student research groups, organisations and associations are active, and the educational offer includes more than 30 fields of study (also with English as a medium of instruction). The Faculty of Materials Science and Engineering (FMSE) is the leading research and higher education institution in Poland. FMSE combines a strong interest in new materials and technologies with significant achievements in applied science.

Role in MgSafe

  • Work Package leader of WP3
  • Host of ESR 9: Diana Martinez
  • Research topic: Quantitative structure and microstructure characterisation and modelling, degradation, corrosion and wear.
  • Scientific part in MgSafe: Ex vivo characterisation of surface and corrosion layer (WP3)

Contact:

  • Wojciech Święszkowski (supervisor ESR)
  • Tomasz Płociński (PI, co-supervisor)

 


MRI.T

MRITools GmbH


Country: Germany
Scientist-in-Charge: Prof. Dr. T. Niendorf
Website: MRI.T

General description
MRI.TOOLS GmbH is an SME that designs, develops, manufactures and delivers solutions for clinical and preclinical biomedical imaging to meet the needs of the ever-growing market of medical technology. MRI.T’s main focus is on research & development, sales and services of innovative hardware and novel technology for magnetic resonance imaging (MRI), computed tomography (CT) and positron emission tomography (PET). MRI.T’s product portfolio encompasses enabling radiofrequency (RF) antennae tailored for a broad range of MR applications. MRI.T is also very proud to offer services for MR compatibility tests, MR safety validation and certification of medical devices and passive conductive implants. For this purpose, MRI.T builds on more than 25 personnel years of experience in MRI science and industry.

Role in MgSafe

  • Host of ESR 13: Mostafa Berangi
  • Speciality: Solutions for clinical and preclinical biomedical (MR) imaging
  • Scientific part in MgSafe: MR safety, MR antenna design (WP4)

Contact:

  • Thoralf Niendorf (supervisor ESR)
  • André Kühne (PI)

 


SYN

Syntellix AG


Country: Germany
Scientist-in-Charge: Dr. J.-M. Seitz
Website: SYN

General description
Research, development and marketing of highly innovative bioabsorbable metallic implants made of magnesium alloys. Syntellix supervises a competence network with partners from material sciences, manufacturing, cleaning, packaging and clinical application, knowledge in the implant development and especially in the certification processes and regulatory limitations of (Mg-) implants.

Role in MgSafe

  • Host of ESR 14: Jonathan Espiritu
  • Speciality: Bioabsorbable metallic implants for human application
  • Scientific part in MgSafe: MR safety, prediction tool (WP4)

Contact:

  • Katrin Nagel, Jan-Marten Seitz (PIs)

 


SCANCO

Scanco Medical AG


Country: Switzerland
Scientist-in-Charge: Dr. B. Koller
Website: SCANCO

General description
SCANCO Medical AG, a SME in Brüttisellen near Zurich has been a pioneer in the field of high-resolution micro-computed tomography (µCT) for more than three decades. In addition to the hardware, SCANCO provides software for image analysis, measurement service and consulting in the field of bone research in pre-clinical and clinical studies. The many collaborations and involvement in research projects lead to an accumulation of in-depth knowledge that is highly valued by the customers.

Role in MgSafe

  • Host of ESR 12: Marwa Chaabane
  • Speciality: µCT Systems and Solutions
  • Scientific part in MgSafe: Software development and management of multimodal data (WP3)

Contact:

  • Bruno Koller (PI)

 


VSI

FujiFilm Sonosite B.V


Country: Netherlands
Scientist-in-Charge: Dr. J. Jose
Website:  VSI

General description
FUJIFILM VisualSonics, a wholly owned subsidiary of FUJIFILM SonoSite, designs and manufactures Ultra High Frequency ultrasound imaging systems, for both research and clinical use. VSI specifically focuses on Ultra High Frequency (UHF) ultrasound machines. For the first 3cm of a scanned body, UHF ultrasound provides images at much higher resolutions—as fine as 30μm—than other imaging systems currently available. VSI originally introduced its UHF ultrasound technology for use in preclinical research, specifically in small animal models of human disease (e.g. mice or rat models). With UHF ultrasound, researchers can study live animals subjects in real-time, longitudinally, with ill no side effects.

Role in MgSafe

  • Work Package leader of WP4
  • Host of ESR 15: Valeria Grasso
  • Speciality: Real time in vivo imaging systems for preclinical research
  • Scientific part in MgSafe: Develop ultrasound and photoacoustics (USPA) probe for Mg-implants (WP4)

Contact:

  • Jithin Jose, Magdalena Steiner, Katrin Suppelt (PIs)

 


BRI.T

BRI.Tech – BioResorbable Implant Technologies


Country: Austria
Scientist-in-Charge: Dr. J. Eichler
Website: BRI.T

General description
BRI.Tech GmbH orthopaedic implants are used for the surgical treatment of bone fractures. Our implants are made of a patented magnesium-based alloy which dissolves over time during the healing process. The focus is on CE Certification, market entrance and coordination of further R&D activities. A quality management system according to ISO13485 which is an essential part for the certification process. The supply chain of BRI.T has been established with ISO13485 certified partners.

Role in MgSafe

  • Speciality: Mg-materials and implants for research purposes
  • Part in MgSafe: Provider of Mg-based implants

Contact:

  • Heinz Moitzi (CTO)
  • Nicole Sommer (Project management and R&D)